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David TW Jones

Publications and source records attributed to David TW Jones.

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TelomereHunter: telomere content estimation and characterization from whole genome sequencing data

SummaryTelomere shortening plays an important role in cellular aging and tumor suppression. The availability of large next-generation sequencing cohorts of matched tumor and control samples enables a computational high-throughput analysis of changes in telomere content and composition in cancer. Here we describe a novel software tool specifically tailored for the processing of large data collections.\n\nAvailability and ImplementationTelomereHunter is implemented as a python package. It is freely available online at: http://www.dkfz.de/en/applied-bioinformatics/telomerehunter/telomerehunter.html.

Bioinformatics