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Ceylan, G.

Publications and source records attributed to Ceylan, G..

2 recordsLinked to original sources

Feature distribution learning by passive exposure

Humans can rapidly estimate the statistical properties of groups of stimuli, including their average and variability. But recent studies of so-called Feature Distribution Learning (FDL) have shown that observers can quickly learn even more complex aspects of feature distributions. In FDL, observers learn the full shape of a distribution of features in a set of distractor stimuli and use this information to improve visual search: response times (RT) are slowed if the target feature lies inside the previous distractor distribution, and the RT patterns closely reflect the distribution shape. FDL requires only a few trials and is markedly sensitive to different distribution types. It is unknown, however, whether our perceptual system encodes feature distributions automatically and by passive exposure, or whether this learning requires active engagement with the stimuli. In two experiments, we sought to answer this question. During an initial exposure stage, participants passively viewed a display of 36 lines that included one orientation singleton or no singletons. In the following search display, they had to find an oddly oriented target. The orientations of the lines were determined either by a Gaussian or a uniform distribution. We found evidence for FDL only when the passive trials contained an orientation singleton. Under these conditions, RTs decreased as a function of the orientation distance between the target and the exposed distractor distribution. These results suggest that FDL can occur by passive exposure, but only if an orientation singleton appears during exposure to the distribution.

neuroscience↗

Comparison of trimethoprim-sulfamethoxazole versus ciprofloxacin monotherapy in Stenotrophomonas maltophilia bloodstream infections in children

Treatment of invasive infections caused by Stenotothromhomas maltophilia is difficult as the bacterium is frequently resistant to a wide range of commonly used antimicrobials. The aim of this retrospective study was to evaluate effectiveness of treatment with ciprofloxacin monotherapy compared to trimethoprim-sulfamethoxazole monotherapy in patients with S. maltophilia infections. We evaluated 50 patients with S. maltophilia bloodstream infections who had received monotherapy with trimethoprim-sulfamethoxazole or ciprofloxacin. Twenty-five patients (50%) received trimethoprim-sulfamethoxazole, and 25 patients (50%) received ciprofloxacin. Thirty-six (72%) patients were in the intensive care unit. All of the patients had at least one indwelling devices and approximately 25% patients had immunosuppression. Ciprofloxacin had the same clinical outcome and mortality as trimethoprim-sulfamethoxazole for the treatment of S. maltophilia bacteremia. In our study; side-effects ratio were not statistically different between ciprofloxacin and trimethoprim-sulfamethoxazole group. Ciprofloxacin could be an alternative drug of choice for treating S. maltophilia infections especially in premature infans in stead of trimethoprim-sulfamethoxazole.

microbiology↗