Alex H Wagner | Search bioRxiv

bioRxiv2016

CIViC: A knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer.

CIViC is an expert crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer (www.civicdb.org) describing the therapeutic, prognostic, and diagnostic relevance of inherited and somatic variants of all types. CIViC is committed to open source code, open access content, public application programming interfaces (APIs), and provenance of supporting evidence to allow for the transparent creation of current and accurate variant interpretations for use in cancer precision medicine.

Cancer Biology↗

bioRxiv2016

GenVisR: Genomic Visualizations in R

SummaryVisualizing and summarizing data from genomic studies continues to be a challenge. Here we introduce the GenVisR package to addresses this challenge by providing highly customizable, publication-quality graphics focused on cohort level genome analyses. GenVisR provides a rapid and easy-to-use suite of genomic visualization tools, while maintaining a high degree of flexibility by leveraging the abilities of ggplot2 and bioconductor.\n\nAvailability and ImplementationGenVisR is an R package available via bioconductor (https://bioconductor.org/packages/GenVisR) under GPLv3. Support is available via GitHub (https://github.com/griffithlab/GenVisR/issues) and the Bioconductor support website.\n\nContactogriffit@genome.wustl.edu, mgriffit@genome.wustl.edu

Bioinformatics↗